Pirina, Pietro and Budroni, Mario and Esposito, Susanna and Ostera, S. and Polo, M. F. and Santoru, Luigi and Madeddu, Giordano and Fois, Alessandro Giuseppe and Ginesu, Giorgio Carlo and Padua, G. and Tanda, Francesco and Ginesu, Francesco (2007) Cytological and histological diagnosis of lung cancer in Sardinia and Italy in the 1990s. Monaldi Archives for Chest Disease, Vol. 67 (4), p. 179-183. ISSN 1122-0643. Article.
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Background. Up to 30-50% of all lung cancer cases remain
without cyto-histological characterisation. The aim
of our study was to evaluate retrospectively the proportion
of histological and/or cytological diagnosis in patients with
lung cancer in Sardinia.
Methods. Data was gathered by consulting the hospital
registers and case notes of individual patients released
from hospital with a diagnosis of Lung Cancer at all medical
centres throughout Sardinia. In gathering patients’
data, we focused our attention on cytological and histological
procedures through which allowed the lung cancer
was diagnosed. Cancer Registries data was utilised to compare
our data with national and Sassari province data.
Results. From 1991 to 1996 there was a total of 3146
lung cancer patients registered in Sardinia. 1902 patients
(60.5%) had a histological diagnosis, 142 patients (4.5%) a
cytological diagnosis while in 1102 patients (35%) the diagnosis
was performed without any pathological validation.
Conclusions. Our study has shown that lung cancer
diagnosis is supported by pathological verification in 65%
of cases while in remaining 35% of patients the diagnosis
is based only on clinical and radiological reports. In Italy
data from Cancer Registries report the percentage of cyto-
histological diagnosis to be 70% with the percentage of
cytological diagnosis being higher than in Sardinia.
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