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A Comparison between the β-globin gene clusters of domestic sheep (Ovis aries) and Sardinian mouflon (Ovis gmelini musimon)

Rando, Andrea and Di Gregorio, Paola and Capuano, M. and Senese, C. and Manca, Laura and Naitana, Salvatore and Masala, Bruno Lucio (1996) A Comparison between the β-globin gene clusters of domestic sheep (Ovis aries) and Sardinian mouflon (Ovis gmelini musimon). Genetics Selection Evolution, Vol. 28 (3), p. 217-222. eISSN 1297-9686. Article.

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Abstract

The organization of the β-globin gene cluster of wild Sardinian mouflons with different haemoglobin phenotypes has been analyzed by means of Southern blot with probes specific for εIV- and βF- globin genes. With three endonucleases (Bam HI, Eco RI, and Hind III), Sardinian mouflons with Hb B, Hb BM and Hb M show identical restriction patterns to sheep with Hb A, Hb AB, and Hb B, respectively. Therefore, in Sardinian mouflons as in domestic sheep, the β-globin gene cluster shows two haplotypes characterized by the triplication or duplication of an ancestral four gene set (ε-ε-ψβ-β).

Item Type:Article
ID Code:4105
Status:Published
Refereed:Yes
Uncontrolled Keywords:Domestic sheep, Sardinian mouflon, haemoglobin, β-globin cluster
Subjects:Area 07 - Scienze agrarie e veterinarie > VET/02 Fisiologia veterinaria
Area 05 - Scienze biologiche > BIO/10 Biochimica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze fisiologiche, biochimiche e cellulari
001 Università di Sassari > 01 Dipartimenti > Biologia animale
Publisher:EDP Sciences
eISSN:1297-9686
Copyright Holders:© Elsevier/INRA
Deposited On:06 Jul 2010 13:53

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