Rando, Andrea and Di Gregorio, Paola and Capuano, M. and Senese, C. and Manca, Laura and Naitana, Salvatore and Masala, Bruno Lucio (1996) A Comparison between the β-globin gene clusters of domestic sheep (Ovis aries) and Sardinian mouflon (Ovis gmelini musimon). Genetics Selection Evolution, Vol. 28 (3), p. 217-222. eISSN 1297-9686. Article.
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The organization of the β-globin gene cluster of wild Sardinian mouflons with different haemoglobin phenotypes has been analyzed by means of Southern blot with probes specific for εIV- and βF- globin genes. With three endonucleases (Bam HI, Eco RI, and Hind III), Sardinian mouflons with Hb B, Hb BM and Hb M show identical restriction patterns to sheep with Hb A, Hb AB, and Hb B, respectively. Therefore, in Sardinian mouflons as in domestic sheep, the β-globin gene cluster shows two haplotypes characterized by the triplication or duplication of an ancestral four gene set (ε-ε-ψβ-β).
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