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Cascade and RCM syntheses of chiral tricyclic alkaloids from (S)-1,2,3,4-tetrahydro isoquinoline carboxylic acid

Muroni, Daniele and Mucedda, Mauro and Saba, Antonio (2009) Cascade and RCM syntheses of chiral tricyclic alkaloids from (S)-1,2,3,4-tetrahydro isoquinoline carboxylic acid. Tetrahedron: Asymmetry, Vol. 20 (10), p. 1154-1159. ISSN 0957-4166. Article.

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DOI: 10.1016/j.tetasy.2009.04.003

Abstract

Concise syntheses of novel chiral pyrroloazacyclo and chiral tricyclic isoquinoline alkaloids, starting from the readily available (S)-1,2,3,4-tetrahydroisoquinoline carboxylic acid methyl ester, by utilizing cascade spiro-to fused and RCM protocols, are reported.

Item Type:Article
ID Code:3809
Status:Published
Refereed:Yes
Uncontrolled Keywords:Chiral tricyclic alkaloids, cascade, RCM syntheses
Subjects:Area 03 - Scienze chimiche > CHIM/06 Chimica organica
Divisions:001 Università di Sassari > 01 Dipartimenti > Chimica
Publisher:Pergamon / Elsevier
ISSN:0957-4166
Copyright Holders:© 2009 Elsevier
Deposited On:03 May 2010 16:16

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