Nieddu, Giammario and De Luca, Lidia Vera Giovanna and Giacomelli, Giampaolo (2008) A Chemoselective, easy bromination of (hydroxymethyl)phenols. Synlett, Vol. 2008 (24), p. 3937-3940. eISSN 1437-2096. Article.
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A simple and chemoselective method for direct bromination of (hydroxymethyl)phenols via reaction with 2,4,6-trichloro[1,3,5]triazine in N,N-dimethylformamide at room temperature is described. The reaction occurs without affecting the phenolic hydroxy group.
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