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Parallel synthesis of trisubstituted formamidines: a facile and versatile procedure

Porcheddu, Andrea and Giacomelli, Giampaolo and Piredda, Ivana (2009) Parallel synthesis of trisubstituted formamidines: a facile and versatile procedure. Journal of Combinatorial Chemistry, Vol. 11 (1), p. 126-130. eISSN 1520-4774. Article.

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DOI: 10.1021/cc8001124


A focused library of formamidines having several diversity points has been prepared. The use of isocyanate resin as scavenger may offer several practical advantages over conventional procedures, such as the ease of workup and availability. The technique described herein was performed in a parallel synthesis format. The whole protocol has potential use in high throughput synthesis for the preparation and purification of libraries of unsymmetrical formamidines containing sets of different aliphatic substituents.

Item Type:Article
ID Code:3651
Uncontrolled Keywords:Formamidines, parallel synthesis, aliphatic substituents
Subjects:Area 03 - Scienze chimiche > CHIM/06 Chimica organica
Divisions:001 Università di Sassari > 01 Dipartimenti > Chimica
Publisher:American Chemical Society
Deposited On:31 Mar 2010 13:48

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