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Risk factors for operated carpal tunnel syndrome: a multicenter population-based case-control study

Mattioli, Stefano and Baldasseroni, Alberto and Bovenzi, Massimo and Curti, Stefania and Cooke, Robin M. T. and Campo, Giuseppe and Barbieri, Pietro G. and Ghersi, Rinaldo and Broccoli, Marco and Cancellieri, Maria Pia and Colao, Anna Maria and Dell'Omo, Marco and Fateh-Moghadam, Pirous and Franceschini, Flavia and Fucksia, Serenella and Galli, Paolo and Gobba, Fabriziomaria and Lucchini, Roberto and Mandes, Anna and Marras, Teresa and Sgarrella, Carla and Borghesi, Stefano and Fierro, Mauro and Zanardi, Francesca and Mancini, Gianpiero and Violante, Francesco S. (2009) Risk factors for operated carpal tunnel syndrome: a multicenter population-based case-control study. BMC Public Health, Vol. 9 (343), p. 1-15. ISSN 1471-2458. Article.

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DOI: 10.1186/1471-2458-9-343


Background. Carpal tunnel syndrome (CTS) is a socially and economically relevant disease caused by compression or entrapment of the median nerve within the carpal tunnel. This population-based case-control study aims to investigate occupational/non-occupational risk factors for surgically treated CTS.
Methods. Cases (n = 220) aged 18-65 years were randomly drawn from 13 administrative databases of citizens who were surgically treated with carpal tunnel release during 2001. Controls (n = 356) were randomly sampled from National Health Service registry records and were frequency matched by age-gender-specific CTS hospitalization rates.
Results. At multivariate analysis, risk factors were blue-collar/housewife status, BMI ≥ 30 kg/m2, sibling history of CTS and coexistence of trigger finger. Being relatively tall (cut-offs based on tertiles: women ≥165 cm; men ≥175 cm) was associated with lower risk. Blue-collar work was a moderate/strong risk factor in both sexes. Raised risks were apparent for combinations of biomechanical risk factors that included frequent repetitivity and sustained force.
Conclusion. This study strongly underlines the relevance of biomechanical exposures in both non-industrial and industrial work as risk factors for surgically treated CTS.

Item Type:Article
ID Code:3540
Uncontrolled Keywords:Carpal tunnel syndrome, occupational risk factors, epidemiology, surgical treatment
Subjects:Area 06 - Scienze mediche > MED/44 Medicina del lavoro
Divisions:002 Altri enti e centri di ricerca del Nord Sardegna > Azienda ASL1, Sassari > SPRESAL-Servizio prevenzione igiene e sicurezza negli ambienti di lavoro
Publisher:BioMed Central
Deposited On:27 Jan 2010 09:50

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