Naitana, Salvatore and Ledda, Sergio and Cocco, Elena and Manca, Laura and Masala, Bruno Lucio (1991) Haemoglobin phenotypes of the wild European mouflon sheep living on the island of Sardinia. Animal Genetics, Vol. 22 (1), p. 67-75. eISSN 1365-2052. Article.
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Haemoglobin (Hb) phenotypes have been studied in 100 wild European mouflons living on the island of Sardinia by means of isoelectric focusing (pH 6.7-7.7 range) of the native tetramers, acid-urea-Triton gel-electrophoresis, and reversedphase HPLC of globin chains. The result indicates the presence of two ß-globin alleles one of which, corresponding to the ßB, being the most common (f=0.94). None were carriers of the earlier described Hb A. The new Hb was provisionally named Hb M. Severely anaemic mouflons were able to synthesize Hb C at expense of the Hb B alone, thus suggesting structural and physiological homologies between mouflon ßB and sheep ßA globin genes, and between the newly observed ßM allele and the ßB of the domestic Sardinian sheep.
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