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Haemoglobin phenotypes of the wild European mouflon sheep living on the island of Sardinia

Naitana, Salvatore and Ledda, Sergio and Cocco, Elena and Manca, Laura and Masala, Bruno Lucio (1991) Haemoglobin phenotypes of the wild European mouflon sheep living on the island of Sardinia. Animal Genetics, Vol. 22 (1), p. 67-75. eISSN 1365-2052. Article.

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Abstract

Haemoglobin (Hb) phenotypes have been studied in 100 wild European mouflons living on the island of Sardinia by means of isoelectric focusing (pH 6.7-7.7 range) of the native tetramers, acid-urea-Triton gel-electrophoresis, and reversedphase HPLC of globin chains. The result indicates the presence of two ß-globin alleles one of which, corresponding to the ßB, being the most common (f=0.94). None were carriers of the earlier described Hb A. The new Hb was provisionally named Hb M. Severely anaemic mouflons were able to synthesize Hb C at expense of the Hb B alone, thus suggesting structural and physiological homologies between mouflon ßB and sheep ßA globin genes, and between the newly observed ßM allele and the ßB of the domestic Sardinian sheep.

Item Type:Article
ID Code:3104
Status:Published
Refereed:Yes
Uncontrolled Keywords:Mouflon, sheep, Hb phenotype, globins, gene frequency, IEF, HPLC, Sardinia
Subjects:Area 07 - Scienze agrarie e veterinarie > VET/10 Clinica ostetrica e ginecologia veterinaria
Area 07 - Scienze agrarie e veterinarie > VET/02 Fisiologia veterinaria
Area 05 - Scienze biologiche > BIO/10 Biochimica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze fisiologiche, biochimiche e cellulari
001 Università di Sassari > 01 Dipartimenti > Patologia e clinica veterinaria
001 Università di Sassari > 01 Dipartimenti > Biologia animale
Publisher:Blackwell / Wiley
eISSN:1365-2052
Publisher Policy:Journal compilation © 2009 Stichting International Foundation for Animal Genetics
Deposited On:09 Oct 2009 12:03

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