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Hematological and biosynthetic features of β0-thalassemia with an associated α-thalassemia heterozygosity in Sardinia

Longinotti, Maurizio Roberto and Masala, Bruno Lucio and Tidore, M. and Falchi, P. P. and Demuro, Pierina and Angius, P. and Dore, Fausto and Pardini, Simonetta and Pranzetti, Paola and Campus, Salvatore (1981) Hematological and biosynthetic features of β0-thalassemia with an associated α-thalassemia heterozygosity in Sardinia. Hemoglobin, Vol. 5 (6), p. 619-625. eISSN 1532-432X. Article.

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DOI: 10.3109/03630268108991695

Abstract

Total hemoglobin, PCV, hemoglobin A2 and hemoglobin F were determined in controls, β0-thal heterozygotes and α-thal+ β thal heterozygotes. Also the distribution of mean corpuscular volume and the mean corpuscular hemoglobin values in Sardinian β0-thal heterozygotes with and without an associated α-thal and the ratio of α/β chain synthesis in β0-thal heterozygotes with or without an associated α-thal were studied.

Item Type:Article
ID Code:3094
Status:Published
Refereed:Yes
Uncontrolled Keywords:β0-thalassemia, α-thalassemia, Sardinia
Subjects:Area 05 - Scienze biologiche > BIO/10 Biochimica
Area 06 - Scienze mediche > MED/15 Malattie del sangue
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze fisiologiche, biochimiche e cellulari
001 Università di Sassari > 03 Istituti > Ematologia
Publisher:Taylor & Francis
eISSN:1532-432X
Deposited On:07 Oct 2009 12:52

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