A Comparative study on the functional properties of the wild European mouflon and domestic sheep hemoglobins

Corda, Marcella and Giardina, Bruno and Pellegrini, Mariagiuseppina and Manca, Laura and Olianas, Alessandra and Sanna, Maria Teresa and Fais, Antonella and Masala, Bruno Lucio (1997) A Comparative study on the functional properties of the wild European mouflon and domestic sheep hemoglobins. Comparative Biochemistry and Physiology. Part B: Biochemistry and Molecular Biology, Vol. 117 (3), p. 417-420. ISSN 1096-4959. Article.

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DOI: 10.1016/S0305-0491(97)00138-7

Abstract

The functional properties of Hb B of the wild European mouflon (Ovis gmelini musimon), Hb B of domestic sheep (Ovis aries), and Hb C isolated from anemic mouflon were investigated. Mouflon and sheep Hbs appear to be very similar in their response to organic anions and protons, whereas sheep Hb B displays an oxygen affinity lower than that of mouflon Hb B and sheep Hb A. Mouflon Hb B and Hb C, like sheep Hb A and Hb C, have similar efficiencies in transporting oxygen to the tissues. As in other ruminant Hbs, the effect of temperature on the oxygen affinity is slight. Data suggest that mouflon Hb B is not only structurally, but even functionally, more similar to sheep Hb A than to sheep Hb B.

Item Type:	Article
ID Code:	3079
Status:	Published
Refereed:	Yes
Uncontrolled Keywords:	Anemia, Bohr effect, mouflon hemoglobin, sheep hemoglobin, oxygen affinity, enthalpy, globin genes
Subjects:	Area 05 - Scienze biologiche > BIO/10 Biochimica
Divisions:	001 Università di Sassari > 01 Dipartimenti > Scienze fisiologiche, biochimiche e cellulari
Publisher:	Elsevier
ISSN:	1096-4959
Deposited On:	01 Oct 2009 13:06

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