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Structure of four newly observed alleles of the adult β-globin gene in Mediterranean goat

Pirastru, Monica and Cherchi, Laura and Serreri, Eva and Hadjisterkotis, Eleftherios and Manca, Laura and El-Sherbini, El Said and Masala, Bruno Lucio (2002) Structure of four newly observed alleles of the adult β-globin gene in Mediterranean goat. Zeitschrift für Jagdwissenschaft, Vol. 48 (Suppl. 1), p. 267-273. ISSN 0044-2887. Article.

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DOI: 10.1007/BF02192417


Owing to the presence of several variants at the adult β-locus and at both α-globinloci, the Hb polymorphism in goat is remarkably complex. We recently confirmed this high polymorphism in a survey on some 400 goats from Sardinia, Egypt and Cyprus. Eight alleles at the β-adultlocus and two allelic genes at both α-globinloci have been detected by electrophoretic and Chromatographic techniques. Five of the β genes identified have been completely sequenced. Four of them produce globin chains already described in previous studies at the protein level, whereas the globin chain encoded by the remaining one was undescribed. Results at the coding and non-coding regions level provide a possible basis for further interpretations on the origin of these alleles.

Item Type:Article
ID Code:3056
Uncontrolled Keywords:Goat, hemoglobin, β-globin genes, Mediterranean area, Sardinia
Subjects:Area 05 - Scienze biologiche > BIO/10 Biochimica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze fisiologiche, biochimiche e cellulari
Publisher:Springer Berlin / Heidelberg
Additional Information:Paper presented at the 25th International Congress of the International Union of Game Biologists (IUGB) and the 9th International Symposium Perdix, Lemesos, Cyprus, 3-7 September 2001.
Deposited On:28 Sep 2009 11:16

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