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Targeting HIV-1 integrase zinc binding motif

Sechi, Mario and Carcelli, Mauro and Rogolino, Dominga and Neamati, Nouri (2009) Targeting HIV-1 integrase zinc binding motif. In: Supuran, Claudiu T. and Winum, Jean-Yves (eds). Drug design of zinc-enzyme inhibitors: functional, structural, and disease applications, Hoboken, Wiley. p. 911-936. ISBN 978-0-470-27500-9. Book Section.

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Abstract

This chapter focuses on the biology of IN, with a particular emphasis on the N-terminal domain, and on the design of prototypes of IN inhibitors targeting this site.

Item Type:Book Section
ID Code:3008
Status:Published
Uncontrolled Keywords:AIDS, zinc enzymes, therapeutic use, IN inhibitors
Subjects:Area 03 - Scienze chimiche > CHIM/08 Chimica farmaceutica
Divisions:001 Università di Sassari > 01 Dipartimenti > Farmaco, chimico, tossicologico
Publisher:Wiley
ISBN:978-0-470-27500-9
Deposited On:28 Sep 2009 10:05

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