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Attività antibatterica in vitro della fosfonomicina

Giola, L. and Rizzu, D. and Zanetti, Stefania Anna Lucia (1978) Attività antibatterica in vitro della fosfonomicina. Giornale di batteriologia, virologia ed immunologia, Vol. 71 (1-6), p. 34-40. ISSN 0390-5462. Article.

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Abstract

We have studied the "in vitro" antibacterial activity of phosphonomycin against 93 freshly isolated bacterial strains. Phosphonomycin posses a good activity mainly against Gram positive bacteria. A marked increase in the antibacterial activity "in vitro" is obtained when phosphonomycin is combined with other antibitoics having a similar mechanism of action (i.e. inhibition of cell-wall synthesis). We have also determined the frequency of phosphonomycin-resistant mutants in some of the strains tested for antibacterial activity. High frequency of resistant strains have found in Klebsiella spp.

Item Type:Article
ID Code:2941
Status:Published
Refereed:Yes
Uncontrolled Keywords:Fosfomycin, antibacterial activity, Gram positive bacteria
Subjects:Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
Publisher:Ospedale Maria Vittoria
ISSN:0390-5462
Deposited On:09 Sep 2009 11:27

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