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Adhesion of mucoid uropathogenic strains of Pseudomonas aeruginosa to HEp-2 cells

Zanetti, Stefania Anna Lucia and Angioi, A. and Fiori, Pier Luigi and Fadda, Giovanni (1994) Adhesion of mucoid uropathogenic strains of Pseudomonas aeruginosa to HEp-2 cells. New Microbiologica, Vol. 17 (4), p. 297-305. ISSN 1121-7138. Article.

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Abstract

We studied a pili-independent adhesion mechanism to HEp-2 cells present in mucoid uropathogenic strains of Pseudomonas aeruginosa. Our data demonstrate that bacterial adhesion to HEp-2 cell surfaces is time dependent and that the phenotypes involved are influenced by bacterial growth conditions. Sonicated bacterial extracts competitively inhibit the adherence of homologous strains to HEp-2 cells. Adhesins that are heat and trypsin sensitive are located on the surface of the bacterial outer membrane. Immunogenic 55 kDa surface protein is required for the adherence to HEp-2 cell surfaces of non-piliated mucosal uropathogenic P. aeruginosa strains.

Item Type:Article
ID Code:2940
Status:Published
Refereed:Yes
Uncontrolled Keywords:Bacterial adhesion, HEp-2 cells, Pseudomonas aeruginosa
Subjects:Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
Publisher:Edizioni internazionali
ISSN:1121-7138
Deposited On:09 Sep 2009 11:26

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