UnissResearch

Logo Universitàegli studi di Sassari
titoli, abstracts, parole chiave >>>
1,2,3-triazolo[4,5-f]quinolines: II: preparation and antimicrobial evaluation of 6-ethyl-6,9-dihydro-1(2)(3)-R-1(2) (3)H-triazolo [4,5-f]quinolin-9-one-8-carboxylic acids as anti-infectives of the urinary tract

Nuvole, Antonio Michele and Sanna, Paolo Antonio and Paglietti, Giuseppe and Juliano, Claudia Clelia Assunta and Zanetti, Stefania Anna Lucia and Cappuccinelli, Pietro Antonio (1989) 1,2,3-triazolo[4,5-f]quinolines: II: preparation and antimicrobial evaluation of 6-ethyl-6,9-dihydro-1(2)(3)-R-1(2) (3)H-triazolo [4,5-f]quinolin-9-one-8-carboxylic acids as anti-infectives of the urinary tract. Il Farmaco, Vol. 44 (6), p. 619-632. ISSN 0014-827X. Article.

[img]
Preview
Full text disponibile come PDF Richiede visualizzatore di PDF come GSview, Xpdf o Adobe Acrobat Reader - Published Version
4Mb

Alternative URLs:

Abstract

Some 6-ethyl-1(2)(3)-R-1(2)(3)H-triazolo[4,5-f]quinolin-9-one-8-carboxylic acids were prepared as novel analogues of oxolinic acid in order to evaluate the effect on antibacterial activity of the isosteric replacement of the dioxolic moiety with the triazole ring substituted in position 1 or 2. In vitro tests showed a good and selective activity against Escherichia coli (MIC 12.5 micrograms/ml) of compound (XVI).

Item Type:Article
ID Code:2928
Status:Published
Refereed:Yes
Uncontrolled Keywords:1,2,3-triazolo[4,5-f]quinolines, antibacterial activity, Escherichia coli
Subjects:Area 03 - Scienze chimiche > CHIM/09 Farmaceutico tecnologico applicativo
Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
Area 03 - Scienze chimiche > CHIM/08 Chimica farmaceutica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
001 Università di Sassari > 01 Dipartimenti > Farmaco, chimico, tossicologico
001 Università di Sassari > 01 Dipartimenti > Scienze del farmaco
Publisher:Società chimica italiana
ISSN:0014-827X
Publisher Policy:Depositato per gentile concessione dell'Editore
Deposited On:09 Sep 2009 09:02

I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore

Repository Staff Only: item control page