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Nuvole, Antonio Michele and Sanna, Paolo Antonio and Paglietti, Giuseppe and Juliano, Claudia Clelia Assunta and Zanetti, Stefania Anna Lucia and Cappuccinelli, Pietro Antonio (1989) 1,2,3-triazolo[4,5-f]quinolines: II: preparation and antimicrobial evaluation of 6-ethyl-6,9-dihydro-1(2)(3)-R-1(2) (3)H-triazolo [4,5-f]quinolin-9-one-8-carboxylic acids as anti-infectives of the urinary tract. Il Farmaco, Vol. 44 (6), p. 619-632. ISSN 0014-827X. Article. Full text not available from this repository. Alternative URLs: AbstractSome 6-ethyl-1(2)(3)-R-1(2)(3)H-triazolo[4,5-f]quinolin-9-one-8-carboxylic acids were prepared as novel analogues of oxolinic acid in order to evaluate the effect on antibacterial activity of the isosteric replacement of the dioxolic moiety with the triazole ring substituted in position 1 or 2. In vitro tests showed a good and selective activity against Escherichia coli (MIC 12.5 micrograms/ml) of compound (XVI).
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