Deidda, Delia and Lampis, Giorgio and Fioravanti, Rossella and Biava, Mariangela and Porretta, Giulio Cesare and Zanetti, Stefania Anna Lucia and Pompei, Raffaello (1998) Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacterium tuberculosis strains. Antimicrobial Agents and Chemotherapy, Vol. 42 (11), p. 3035-3037. eISSN 1098-6596. Article.
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The pyrrole derivative BM212 [1,5-diaryl-2-methyl-3-(4-methylpiperazin-1-yl)methyl-pyrrole] was shown to possess strong inhibitory activity against both Mycobacterium tuberculosis and some nontuberculosis mycobacteria. BM212 was inhibitory to drug-resistant mycobacteria and also exerted bactericidal activity against intracellular bacilli residing in the U937 human histiocytic lymphoma cell line.
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