Aceti, Antonio and Zanetti, Stefania Anna Lucia and Mura, Maria Stella Anna and Sechi, Leonardo Antonio and Turrini, Francesco Michelangelo and Saba, Franca and Babudieri, Sergio and Mannu, Franca and Fadda, Giovanni (1999) Identification of HIV patients with active pulmonary tuberculosis using urine based polymerase chain reaction assay. Thorax, Vol. 54 (2), p. 145-146. eISSN 1468-3296. Article.
BACKGROUND Despite the increased dissemination of tuberculosis among HIV infected patients, the diagnosis is difficult to establish. Traditional microbiological methods lack satisfactory sensitivity. We have developed a highly sensitive and specific nested polymerase chain reaction (PCR) capable of detecting Mycobacterium tuberculosis DNA in urine specimens and have used this test to examine urine specimens from HIV patients with active pulmonary tuberculosis.
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