Deriu, Antonella and Branca, Giovanna and Molicotti, Paola and Pintore, Giorgio Antonio Mario and Chessa, Mario and Tirillini, Bruno and Paglietti, Bianca and Mura, Antonio and Sechi, Leonardo Antonio and Fadda, Guido and Zanetti, Stefania Anna Lucia (2007) In vitro activity of essential oil of Myrtus communis L. against Helicobacter pylori. International Journal of Antimicrobial Agents, Vol. 30 (6), p. 562-563. ISSN 0924-8579. Article.
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We recently investigated the antimicrobial properties of the essential oil of Myrtus communis L. against clinical isolates of Helicobacter pylori collected in the Institute of Microbiology of the Catholic University of the Sacred Heart in Rome, Italy. H. pylori is now a well-recognized cause of chronic active gastritis, peptic ulcer disease, gastric carcinoma and gastric mucosa-associated lymphatic tissue lymphomas or MALTomas, and its eradication is strongly recommended for patients with these diseases and those with unexplained iron deficiency anaemia. Current treatment for H. pylori infections includes an antisecretory agent plus two or more of the following antibiotics: amoxicillin, clarithromycin, nitroimidazoles, tetracycline and levofloxacin. Strains displaying primary resistance to nitroimidazoles and clarithromycin are being reported with increasing frequency throughout the world. Together with noncompliance, antibiotic resistance is a major cause of treatment failure in patients with these infections. For this reason, we assessed the effects of the essential oil of M. communis on the growth and survival of H. pylori.
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