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Genotypic changes in DNA fingerprinting patterns of Mycobacterium tuberculosis strains from HIV-positive persons in Sardinia

Sechi, Leonardo Antonio and Zanetti, Stefania Anna Lucia and Duprè, Ilaria and Aceti, Antonio and Sanguinetti, Maurizio and Fadda, Giovanni (1998) Genotypic changes in DNA fingerprinting patterns of Mycobacterium tuberculosis strains from HIV-positive persons in Sardinia. AIDS, Vol. 12 (15), p. 2084-2086. eISSN 1473-5571. Article.

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Abstract

Amongst infectious diseases, tuberculosis is still the major killer in the world. In some developing countries tuberculosis infection has reached epidemic proportions and is increasing worldwide. This rapid growth is thought to be correlated in part to the movement of people from developing countries, where tuberculosis largely occurs, to industrialized countries. It is also due in part to AIDS, as Mycobacterium tuberculosis infection appears to be one of the first indications of a loss of immune system function, and those infected are susceptible to a number of opportunistic infections, including infections by other mycobacteria, and finally because the expectation of life is increased. In the present study, we applied a computer-assisted method to analyse DNA fingerprints and construct dendrograms of M. tuberculosis strains isolated from HIV-positive patients.

Item Type:Article
ID Code:2827
Status:Published
Refereed:Yes
Uncontrolled Keywords:Fingerprint method, Mycobacterium tuberculosis, AIDS, Sardinia
Subjects:Area 06 - Scienze mediche > MED/17 Malattie infettive
Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
001 Università di Sassari > 03 Istituti > Malattie infettive e parassitarie
Publisher:Lippincott Williams & Wilkins
eISSN:1473-5571
Deposited On:03 Sep 2009 13:37

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