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Tall stories: the devilish detail of genetic association studies

Tomasi, Paolo (2004) Tall stories: the devilish detail of genetic association studies. Clinical Endocrinology, Vol. 60 (3), p. 394. eISSN 1365-2265. Article.

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DOI: 10.1111/j.1365-2265.2004.01996.x

Abstract

I think that clinicians should be wary about association studies in general, unless they are repeatedly confirmed by independent studies. Authors, for their part, should state how many markers they have studied in total, and discuss the implications of applying (or not applying) the Bonferroni correction to their results. These aspects might perhaps be implicit for population geneticists, but possibly not so obvious for the general clinician.

Item Type:Article
ID Code:2540
Status:Published
Refereed:Yes
Uncontrolled Keywords:Genetic association studies, SNPs
Subjects:Area 06 - Scienze mediche > MED/09 Medicina interna
Divisions:001 Università di Sassari > 03 Istituti > Clinica medica generale e terapia medica
Publisher:Blackwell / Wiley
eISSN:1365-2265
Copyright Holders:© 2004 Blackwell
Deposited On:18 Aug 2009 10:08

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