Ulgheri, Fausta and Marchetti, Mauro and Piccolo, Oreste (2007) Enantioselective synthesis of (S)- and (R)-tolterodine by asymmetric hydrogenation of a coumarin derivative obtained by a Heck reaction. The Journal of Organic Chemistry, Vol. 72 (16), p. 6056-6059. eISSN 1520-6904. Article.
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An efficient and short enantioselective synthesis of (S)- and (R)-tolterodine was performed by asymmetric hydrogenation of a coumarin intermediate, easily obtained by a Heck reaction from inexpensive and commercially available starting materials.
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