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Discoid lupus erythematosus of the eyelids associated with staphylococcal blepharitis and Meibomian gland dysfunction

Ena, Pasquale and Pinna, Antonio <1963- > and Carta, Francesco (2006) Discoid lupus erythematosus of the eyelids associated with staphylococcal blepharitis and Meibomian gland dysfunction. Clinical and Experimental Dermatology, Vol. 31 (1), p. 77-79. eISSN 1365-2230. Article.

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DOI: 10.1111/j.1365-2230.2005.01988.x

Abstract

Lower eyelid involvement occurs in 6% of patients with discoid lupus erythematosus (DLE). Eyelid lesions are rarely the initial manifestation of DLE. We describe a 25-yearold woman presenting with discoid lesions of the lower eyelids, staphylococcal blepharitis and Meibomian gland dysfunction, who later developed a discoid lesion on the chin. Histopathological and immunofluorescence studies of a biopsy specimen from this lesion established the diagnosis of DLE. We are unaware of any previously reported cases of DLE presenting with discoid eyelid lesions associated with staphylococcal blepharitis and Meibomian gland dysfunction. DLE should be considered as a differential diagnosis in chronic blepharitis that persists despite usual medical management and eyelid hygiene. Misdiagnosis may lead to eyelid margin deformities, necessitate a complicated full-thickness biopsy, and delay diagnosis of systemic lupus.

Item Type:Article
ID Code:2411
Status:Published
Refereed:Yes
Uncontrolled Keywords:Discoid lupus erythematosus, discoid eyelid lesions
Subjects:Area 06 - Scienze mediche > MED/35 Malattie cutanee e veneree
Area 06 - Scienze mediche > MED/30 Malattie apparato visivo
Divisions:001 Università di Sassari > 03 Istituti > Dermatologia
001 Università di Sassari > 03 Istituti > Oftalmologia, Otorinolaringoiatria e Urologia
Publisher:Blackwell / Wiley
eISSN:1365-2230
Copyright Holders:© 2005 Blackwell
Deposited On:18 Aug 2009 10:07

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