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Two cases of human granulocytic Ehrlichiosis in Sardinia, Italy confirmed by PCR

Mastrandrea, Scilla and Mura, Maria Stella Anna and Tola, Sebastiana and Patta, Cristiana and Tanda, A. and Porcu, R. and Masala, Giovanna (2006) Two cases of human granulocytic Ehrlichiosis in Sardinia, Italy confirmed by PCR. Annals of the New York Academy of Sciences, Vol. 1078 , p. 548-551. eISSN 1749-6632. Article.

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DOI: 10.1196/annals.1374.107


In this work we report the first two cases of human granulocytic ehrlichiosis (HGE) in Sardinia. In early September 2004, a 69-year-old woman (patient 1) was admitted to the Infectious Diseases Institute of Sassari for rickettsiosis like-syndrome: high fever (39.5-40°C), dyspnea, reduced consciousness, vomiting, and cutaneous rash. In late September 2004, a 30-year-old man (patient 2) with high fever was admitted for an evident palmar and oral erythema, edema of the labium, very intense arthralgia, myalgia, and dyspnea. In these two hospitalized patients, the diagnosis was made through indirect IgM and IgG immunofluorescent technique and confirmed by the presence of the specific DNA in the leukocytes. The two patients were A. phagocytophilum-PCR positive.

Item Type:Article
ID Code:2374
Uncontrolled Keywords:A. phagocytophilum, granulocytic ehrlichiosis, Sardinia, Italy
Subjects:Area 06 - Scienze mediche > MED/17 Malattie infettive
Divisions:002 Altri enti e centri di ricerca del Nord Sardegna > Istituto zooprofilattico sperimentale della Sardegna, Sassari
001 Università di Sassari > 03 Istituti > Malattie infettive e parassitarie
Publisher:Blackwell / Wiley
Copyright Holders:© 2006 The New York Academy of Sciences
Deposited On:18 Aug 2009 10:07

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