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Performance of QuantiFERON-TB testing in a tuberculosis outbreak at a Primary school

Molicotti, Paola and Bua, Alessandra and Mela, Maria Graziella and Olmeo, Paolina and Delogu, Renzo and Ortu, Silvia and Sechi, Leonardo Antonio and Zanetti, Stefania Anna Lucia (2008) Performance of QuantiFERON-TB testing in a tuberculosis outbreak at a Primary school. The Journal of Pediatrics, Vol. 152 (4), p. 585-586. ISSN 0022-3476. Article.

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DOI: 10.1016/j.jpeds.2007.12.014

Abstract

This study compared the effectiveness of the QuantiFERON-TB Gold (QFT) assay with the Mantoux tuberculin skin test to detect Mycobacterium tuberculosis infection in 29 children during a school outbreak of tuberculosis. Of the 21 children with M tuberculosis infection, 11 had a radiograph suggestive of the infection. The QFT assay was positive in all 21 of the children, and the Mantoux test was negative at first testing in 2 children (1 of whom was the sentinel case). The findings demonstrate that the QFT test is extremely useful in accurately identifying infected and uninfected children, permitting rapid intervention.

Item Type:Article
ID Code:2016
Status:Published
Refereed:Yes
Uncontrolled Keywords:QuantiFERON-TB Gold (QFT), Mycobacterium tuberculosis infection, Mantoux test
Subjects:Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
001 Università di Sassari > 01 Dipartimenti > Neuroscienze, scienze materno infantili
001 Università di Sassari > 01 Dipartimenti > Scienze ambientali agrarie e biotecnologie agro-alimentari
Publisher:Mosby
ISSN:0022-3476
Deposited On:18 Aug 2009 10:06

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