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Spontaneous regression of hepatocellular carcinoma: report of a case

Feo, Claudio F. and Marrosu, Antonio and Scanu, Antonio Mario and Ginesu, Giorgio Carlo and Fancellu, Alessandro and Migaleddu, Vincenzo and Porcu, Alberto (2004) Spontaneous regression of hepatocellular carcinoma: report of a case. European Journal of Gastroenterology & Hepatology, Vol. 16 (9), p. 933-936. ISSN 0954-691X. Article.

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The widespread use of ultrasound in screening programmes for chronic liver disease has led to early diagnosis of hepatocellular carcinoma (HCC), and to the observation of some cases of tumour spontaneous regression. This is a rare event whose underlying mechanism is still unclear. We present here a case of spontaneous regression of HCC in a 71-year-old woman with chronic hepatitis and discuss possible aetiologies. None of the causative mechanisms proposed for spontaneous regression of HCC is completely satisfactory, so further studies are necessary to improve understanding of this unusual biological event. Therefore, we stress the importance of accumulating all such cases in the literature, because the clarification of aetio-pathogenic mechanisms may lead to the development of new treatment strategies for HCC.

Item Type:Article
ID Code:196
Uncontrolled Keywords:Hepatocellular carcinoma, spontaneous regression, liver, neoplasms
Subjects:Area 06 - Scienze mediche > MED/18 Chirurgia generale
Divisions:002 Altri enti e centri di ricerca del Nord Sardegna > SMIRG-Sardinian Mediterranean Imaging Research Group, Sassari
001 Università di Sassari > 03 Istituti > Clinica chirurgica generale e terapia chirurgica
Publisher:Lippincott Williams & Wilkins
Deposited On:18 Aug 2009 10:01

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