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Carbamazepine, clonazepam and focal reflex proprioceptive seizures

Sechi, Gianpietro and Corda, Davide and Deiana, Giovanni Andrea and Contu, Sabrina and Rosati, Giulio (2003) Carbamazepine, clonazepam and focal reflex proprioceptive seizures. Clinical Neuropharmacology, Vol. 26 (6), p. 327-330. ISSN 0362-5664. Article.

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We studied a 34-year-old man with focal tonic-clonic seizures sometimes elicited by some active postures of the right hand and evolving at times to secondary generalization. Treatment with carbamazepine (CBZ) in combination with parenteral diazepam induced both a dramatic increase of focal reflex proprioceptive seizures and choreoathetoid dyskinesias in the affected hand. CBZ was withdrawn and clonazepam (CZP) given 2 mg daily, with complete relief of seizures and choreoathetoid dyskinesias. CZP had a suppressive effect on seizures for over 15 years, without development of tolerance.

Item Type:Article
ID Code:195
Uncontrolled Keywords:Carbamazepine, clonazepam, reflex-proprioceptive seizures
Subjects:Area 06 - Scienze mediche > MED/26 Neurologia
Divisions:001 Università di Sassari > 03 Istituti > Clinica neurologica
Publisher:Lippincott Williams & Wilkins
Deposited On:18 Aug 2009 10:01

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