Pinna, Antonio <1963- > and Simula, P. and Salvo, Marco Michele and Devilla, L. and Zinellu, Angelo and Carta, Arturo (2008) Subcutaneous nadroparin calcium in the treatment of retinal vein occlusion. Acta Ophthalmologica, Vol. 86 (s243), 0-0. eISSN 1755-3768. Article.
Full text not available from this repository.
Purpose: To date, no systemic intervention has been demonstrated to favorably affect the natural history of retinal vein occlusion (RVO). The purpose of this study was to evaluate the efficacy of nadroparin calcium in the treatment of RVO. Methods: 13 patients with acute RVO (i.d. within a week of onset) were treated with subcutaneous injections of nadroparin calcium for 2 months. The same dose used for the treatment of deep venous thrombosis (200UI/kg/die) was given. Best corrected visual acuity (BCVA) in the affected eye was measured at baseline and after 3 months. In addition, macular thickness was measured by Stratus OCT (Carl Zeiss Meditec, USA) at baseline and after 3 months. Results: Mean visual acuity was 0.39±0.33 at baseline and 0.70±0.32 after 3 months; differences were statistically significant (P=0.024). Macular thickness was measured in 8 patients; mean thickness was 510±239 μm at baseline and 331±190 μm after 3 months; differences were not statistically significant (P=0.12). After 3 months, fluorescein angiography disclosed no signs of retinal ischemia in all cases. Conclusion: This preliminary study suggest that subcutaneous nadroparin calcium may be effective in the treatment of RVO. Larger long-term studies are warranted to confirm this results.
I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore
Repository Staff Only: item control page