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Brain Parenchyma Sonography (BPS) of Substantia Nigra (SN) in Parkinson's disease

Zedde, Maria Luisa and Manca, A. and Baule, Giovanni Maria and Agnetti, Virgilio (2005) Brain Parenchyma Sonography (BPS) of Substantia Nigra (SN) in Parkinson's disease. Parkinsonism & Related Disorders, Vol. 11 (Suppl. 2), p. 222. ISSN 1353-8020. Article.

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DOI: 10.1016/S1353-8020(05)80121-X

Abstract

Idiopatic Parkinson's disease (IPD) is the most common neurodegenerative movement disorder. Others closely related parkinsonian disorders, like corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP), share many clinical features, such as rapid disease progression, poor levodopa response, eye movement abnormalities, cognitive impairment, apraxia, pyramidal signs, and dystonia. These similarities often cause difficulty in clinical differentiation, especially in their early course. Traditional neuroimaging methods, such as MRI, SPET, and PET, may improve diagnostic accuracy, but not in early stages or even in the preclinical stage of the nigrostriatal degeneration, except maybe PET. However, these techniques are expensive, and largely unavailable for routine diagnostic workup.

Item Type:Article
ID Code:1492
Status:Published
Refereed:Yes
Uncontrolled Keywords:Brain Parenchyma Sonography (BPS), Substantia Nigra (SN), neuroimaging, Parkinson's disease
Subjects:Area 06 - Scienze mediche > MED/26 Neurologia
Divisions:002 Altri enti e centri di ricerca del Nord Sardegna > Azienda ASL1, Sassari > Ospedale civile SS. Annunziata
001 Università di Sassari > 03 Istituti > Clinica neurologica
Publisher:Elsevier
ISSN:1353-8020
Additional Information:Poster presented at the 16. International Congress on Parkinson's Disease and Related Disorders. Berlin, Germany, June 5-9, 2005.
Deposited On:18 Aug 2009 10:05

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