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Synchronous interdigitating dendritic cell sarcoma and B-cell small lymphocytic lymphoma in a lymph node

Cossu, Antonio and Deiana, Angelo and Lissia, Amelia and Dedola, Maria Filomena and Cocco, Lucia and Palmieri, Giuseppe and Tanda, Francesco (2006) Synchronous interdigitating dendritic cell sarcoma and B-cell small lymphocytic lymphoma in a lymph node. Archives of Pathology and Laboratory Medicine, Vol. 130 , p. 544-547. ISSN 1543-2165. Article.

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A gradually enlarging axillary mass in a 79-year-old man was excised. The specimen was processed for light microscopy, immunohistochemical studies, and electron microscopy; gene rearrangement studies were also performed. A diagnosis of an interdigitating dendritic cell tumor of the lymph node and a B-cell small lymphocytic lymphoma occurring in the same anatomic location was made. We found that although rare cases of interdigitating dendritic cell tumor with an associated secondary malignancy have been described in the literature, to our knowledge, this is the first report of interdigitating dendritic cell tumor and synchronous neoplasm diagnosed at the same site. A possible relationship between the 2 disorders is also discussed.

Item Type:Article
ID Code:1429
Uncontrolled Keywords:Dendritic cells (DCs), B-cells, sarcoma
Subjects:Area 06 - Scienze mediche > MED/08 Anatomia patologica
Divisions:001 Università di Sassari > 03 Istituti > Anatomia patologica
002 Altri enti e centri di ricerca del Nord Sardegna > CNR-Consiglio Nazionale delle Ricerche > Istituto di chimica biomolecolare, Sassari
Publisher:College of American Pathologists
Publisher Policy:Depositato per gentile concessione dell'Archives of Pathology & Laboratory Medicine.
Deposited On:18 Aug 2009 10:05

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