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Antibacterial activity of ozonized sunflower oil (Oleozon)

Sechi, Leonardo Antonio and Lezcano, Irene and Nunez, N. and Espim, M. and Duprè, Ilaria and Pinna, Antonio <1963- > and Molicotti, Paola and Fadda, Guido and Zanetti, Stefania Anna Lucia (2001) Antibacterial activity of ozonized sunflower oil (Oleozon). Journal of Applied Microbiology, Vol. 90 (2), p. 279-284. eISSN 1365-2672. Article.

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DOI: 10.1046/j.1365-2672.2001.01235.x

Abstract

Aims: To evaluate the antimicrobial effect of the ozonized sunflower oil (Oleozon) on different bacterial species isolated from different sites.
Methods and Results: The effect of Oleozon on Mycobacteria, staphylococci, streptococci, enterococci, Pseudomonas and Escherichia coli was tested. The sunflower oil was ozonized at the Centro de Investigaciones del Ozone (CENIC, Havana, Cuba) by an ozone generator. MICs were determined by the agar dilution method. For Mycobacteria, the MIC of Oleozon was determined on solid medium by a microdrop agar proportion test. Oleozon showed antimicrobial activity against all strains analysed, with an MIC ranging from 1·18 to 9·5 mg ml−1.
Conclusions: Oleozon showed a valuable antimicrobial activity against all micro-organisms tested. Results suggest that Mycobacteria are more susceptible to Oleozon than the other bacteria tested.
Significance and Impact of the Study: The wide availability of sunflower oil makes Oleozon a competitive antimicrobial agent. These results should prompt the setting up of some clinical trials to compare Oleozon with other antimicrobial agents.

Item Type:Article
ID Code:1347
Status:Published
Refereed:Yes
Uncontrolled Keywords:Oleozon, ozonized sunflower oil, mycobacteria
Subjects:Area 06 - Scienze mediche > MED/30 Malattie apparato visivo
Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
Publisher:The Society for Applied Microbiology
eISSN:1365-2672
Deposited On:18 Aug 2009 10:04

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