titoli, abstracts, parole chiave >>>
"In vitro" activities of antimycobacterial agents against Mycobacterium avium subsp. paratuberculosis linked to Crohn's disease and paratuberculosis

Zanetti, Stefania Anna Lucia and Molicotti, Paola and Cannas, Sara and Ortu, Silvia and Ahmed, Niyaz and Sechi, Leonardo Antonio (2006) "In vitro" activities of antimycobacterial agents against Mycobacterium avium subsp. paratuberculosis linked to Crohn's disease and paratuberculosis. Annals of Clinical Microbiology and Antimicrobials, Vol. 5 (27), p. 1-3. ISSN 1476-0711. Article.

[img]
Preview
Full text disponibile come PDF Richiede visualizzatore di PDF come GSview, Xpdf o Adobe Acrobat Reader
Available under License Creative Commons Attribution.

209Kb

DOI: 10.1186/1476-0711-5-27

Abstract

Crohn's disease, a human disease similar to paratuberculosis in animals is the most painful and devastating disease that may involve infection with M. avium subsp. paratuberculosis (MAP), different genetic polymorphisms and an immune dysregulation syndrome. Treatment of Crohn's disease is most commonly based on 5-aminosalicylic acid (5-ASA) compounds, corticosteroids, and immunosuppressive agents. Recently, biological therapies using monoclonal antibodies against inflammatory cytokines have shown some positive results. However, all these therapies treat the symptoms not the cause of the disease.

Item Type:Article
ID Code:134
Status:Published
Refereed:Yes
Uncontrolled Keywords:MAP, antibiotic activity, Crohn's disease
Subjects:Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
002 Altri enti e centri di ricerca del Nord Sardegna > ISOGEM-International Society for Genomic and Evolutionary Microbiology, Sassari
Publisher:BioMed Central
ISSN:1476-0711
Copyright Holders:© 2006 Zanetti et al; licensee BioMed Central
Deposited On:18 Aug 2009 10:01

I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore

Repository Staff Only: item control page