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Acquired hemophilia in a patient affected by acute myeloid leukemia

Fozza, Claudio and Bellizzi, Saverio and Piseddu, Gavino and Porcu, Alberto and Dore, Fausto and Longinotti, Maurizio Roberto (2005) Acquired hemophilia in a patient affected by acute myeloid leukemia. American Journal of Hematology, Vol. 79 (1), p. 81-82. eISSN 1096-8652. Article.

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DOI: 10.1002/ajh.20323


Acquired hemophilia (AH) is an unusual hemorrhagic syndrome characterized by the occurrence of inhibitors of factor VIII (FVIII) in nonhemophilic patients. It has been found in normal subjects and in patients suffering from autoimmune diseases, cancer[1,2], and chronic lymphoproliferative disorders. AH has also been anecdotally described in patients with myeloid malignancies [3,5]. We describe herein a patient diagnosed with acute myeloid leukemia (AML), in which the occurrence of FVIII inhibitors complicated critical intestinal bleeding.

Item Type:Article
ID Code:1206
Uncontrolled Keywords:Hemophilia, myeloid leukemia
Subjects:Area 06 - Scienze mediche > MED/15 Malattie del sangue
Area 06 - Scienze mediche > MED/18 Chirurgia generale
Divisions:001 Università di Sassari > 03 Istituti > Clinica chirurgica generale e terapia chirurgica
001 Università di Sassari > 03 Istituti > Ematologia
002 Altri enti e centri di ricerca del Nord Sardegna > Azienda ASL1, Sassari > Ospedale civile SS. Annunziata > Centro emofilia e trombosi
Deposited On:18 Aug 2009 10:04

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