Fozza, Claudio and Bellizzi, Saverio and Piseddu, Gavino and Porcu, Alberto and Dore, Fausto and Longinotti, Maurizio Roberto (2005) Acquired hemophilia in a patient affected by acute myeloid leukemia. American Journal of Hematology, Vol. 79 (1), p. 81-82. eISSN 1096-8652. Article.
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Acquired hemophilia (AH) is an unusual hemorrhagic syndrome characterized by the occurrence of inhibitors of factor VIII (FVIII) in nonhemophilic patients. It has been found in normal subjects and in patients suffering from autoimmune diseases, cancer[1,2], and chronic lymphoproliferative disorders. AH has also been anecdotally described in patients with myeloid malignancies [3,5]. We describe herein a patient diagnosed with acute myeloid leukemia (AML), in which the occurrence of FVIII inhibitors complicated critical intestinal bleeding.
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