Donadu, Matthew Gavino (2018) Studio di alcuni oli essenziali nella pratica clinica. Doctoral Thesis.
|Full text disponibile come PDF Richiede visualizzatore di PDF come GSview, Xpdf o Adobe Acrobat Reader|
During the Ph.D. period, mastery of several traditional microbiology techniques, such as bacteriology and cytology, and molecular techniques was acquired, with application on randomized clinical trials.
The research activity has focused mainly on in vitro antibacterial, antioxidant and cytotoxic activity with subsequent application of some essential oils in vivo on animals and on humans.
Considering the results obtained, it is clear that Thymus vulgaris - red thyme geraniol sel and L. grosso oils have shown good antimicrobial activity, compared to L. angustifolia and L. sumian on multi-drug clinical strains of P. aeruginosa.
While L. angustifolia Miller presented a cytotoxic action on CaCo-2 cells (Colon-carcinoma Carcinoma Cells) probably due to the action of terpenes.
The oleolites of Helichrysum microphyllum Cambess. subsp. tyrrhenicum Bacch., Brullo & Giusso and Hypericum perforatum subsp. Angustifolium were tested against 30 strains of Candida spp.: the oleolite of H. microphyllum showed greater antifungal activity compared to H. perforatum.
Finally, the antifungal action of Mirtus communis was studied against 86 strains of Malassezia spp.: the obtained data showed a remarkable activity against M. furfur and M. sympodialis.
Furthermore, an in vivo study was performed and we present here the preliminary data.
The topic developed is part of a research area aimed at the use of essential oils with antibacterial activity in the problem of drug resistance.
I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore
Repository Staff Only: item control page