Cugurullo, Francesca (2018) Follow up prenatale e post natale dei feti IUGR: differenza di genere. Doctoral Thesis.
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Aim: The purpose of this study was to determine if there is a difference in perinatal outcome by gender among growth-restricted fetuses.
Methods: This was a retrospective cohort study of intrauterine growth restriction (IUGR) singleton pregnancies over a one year period. Clinical outcomes compared by gender included preterm delivery, perinatal mortality (PNM), respiratory distress syndrome (RDS), grade 3 or 4 intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), and periventricular leukomalacia (PVL). Statistical analysis included bivariate and multivariable techniques.
Results: One hundred singleton pregnancies with IUGR were identified in our Clinc. Fourtyseven (47.6%) were males. Birth weight was similar between the groups. After adjusting for maternal demographics, medical history, gestational age, mode of delivery, and antenatal corticosteroids, adverse perinatal outcomes were similar between the groups. Severity of outcomes was also similar between males and females.
Conclusion: The general concept that male fetuses have a lower clinical performance than females apparently does not apply in the case of intrauterine growth restriction. The scales are tipped by females, who are more prone to develop IUGR.
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