Nguyen , Hoang Bach (2016) Molecular and antigenetic characterization of Streptococcus suis serotype 2 isolates in Central Vietnam. Doctoral Thesis.
Streptococcus suis is a Gram-positive bacterium with clinical relevance in pigs and is emerging in human. There are 35 S. suis serotypes have been distinguished to date, of which serotype 2 is most commonly associated with disease in human and pigs, worldwide. Recently, S. suis emerged as a zoonotic agent in human in contact with infected pigs or with their products. More recently, several studies from Southeast Asia demonstrated that S. suis can cause adult endocarditis, septicemia, arthritis and especially meningitis with high fatality rate and severe neurological sequelae. Multilocus enzyme electrophoresis, restriction endonuclease analysis with HaeIII, ribotyping, and pulsed-field gel electrophoresis have been used to determine S. suis strains epidemiological relationships. Characterization of the 16S-23S ribosomal (r) DNA intergenic spacer region (ITS) has also been used to compare bacterial strains and to identify species within the genus Streptococcus, including S. suis.
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