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Efficacy of Broadline® spot-on against Aelurostrongylus abstrusus and Troglostrongylus brevior lungworms in naturally infected cats from Italy

Giannelli, Alessio and Brianti, Emanuele and Varcasia, Antonio and Colella, Vito and Tamponi, Claudia and Di Paola, Giancarlo and Knaus, Martin and Halos, Lénaïg and Beugnet, Frederic and Otranto, Domenico (2015) Efficacy of Broadline® spot-on against Aelurostrongylus abstrusus and Troglostrongylus brevior lungworms in naturally infected cats from Italy. Veterinary Parasitology, Vol. 209 (3-4), p. 273-277. ISSN 0304-4017. eISSN 1873-2550. Article.

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DOI: 10.1016/j.vetpar.2015.02.037

Abstract

The increasing reports of Aelurostrongylus abstrusus infection and the new information on Troglostrongylus brevior have spurred the interest of the scientific community towards the research of pharmaceutical compounds effective against both pathogens. A novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel (Broadline®, Merial) has been released for the treatment of a variety of feline parasitic infections. The present study reports the efficacy of this spot-on in treating cats naturally infected by feline lungworms. Client owned cats (n = 191) were enrolled from three geographical areas of Italy and faecal samples were examined by floatation and Baermann techniques. Twenty-three individuals were positive for L1 of A. abstrusus (n = 18) or T. brevior (n = 3) or for both species (n = 2) and they were topically treated with Broadline®. Seventeen of them were also concomitantly infected by other parasites. Four weeks after treatment, faecal samples were collected and examined to assess the efficacy of a single administration of the product. Based on lungworm larvae counts, the efficacy of the treatment was 90.5% or 100% for A. abstrusus or T. brevior, respectively. Cats released significantly lower amounts of lungworm larvae after treatment compared to pre-treatment (p < 0.0001). All but three cats were negative for other nematodes after treatment and all cats recovered from respiratory signs. Results of this study indicate that a single administration of the topical combination fipronil, (S)-methoprene, eprinomectin and praziquantel is effective and safe for the treatment of A. abstrusus and/or T. brevior infections in cats living under field conditions.

Item Type:Article
ID Code:10825
Status:Published
Refereed:Yes
Uncontrolled Keywords:Aelurostrongylus abstrusus, Troglostrongylus brevior, lungworms, Broadline®, gastrointestinal parasites, cats, treatment, co-infections
Subjects:Area 07 - Scienze agrarie e veterinarie > VET/06 Parassitologia e malattie parassitarie degli animali
Divisions:001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Medicina Veterinaria
Publisher:Elsevier
ISSN:0304-4017
eISSN:1873-2550
Deposited On:12 Mar 2015 14:23

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