Ganau, Antonello and Devereux, Richard B. and Roman, Mary J. and De Simone, Giovanni and Pickering, Thomas G. and Saba, Pier Sergio and Vargiu, Paolo and Simongini, Isabella and Laragh, John H. (1992) Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension. Journal of the American College of Cardiology, Vol. 19 (7), p. 1550-1558. ISSN 0735-1097. eISSN 1558-3597. Article.
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The spectrum of left ventricular geometric adaptation to hypertension was investigated in 165 patients with untreated essential hypertension and 125 age- and gender-matched normal adults studied by two-dimensional and M-mode echocardiography. Among hypertensive patients, left ventricular mass index and relative wall thickness were normal in 52%, whereas 13% had increased relative wall thickness with normal ventricular mass (“concentric remodeling”), 27% had increased mass with normal relative wall thickness (eccentric hypertrophy) and only 8% had “typical” hypertensive concentric hypertrophy (increase in both variables).
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