Dolei, Antonina and Serra, Caterina and Mameli, Giuseppe and Pugliatti, Maura and Sechi, Gianpietro and Cirotto, M.C. and Rosati, Giulio and Sotgiu, Stefano (2002) Multiple sclerosis–associated retrovirus (MSRV) in Sardinian MS patients. Neurology, Vol. 58 (3), p. 471-473. ISSN 0028-3878. eISSN 1526-632X. Article.
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Blood and CSF of Sardinian patients with MS and neurologic control subjects were tested for MS-associated retrovirus (MSRV). CSF detection in MS was 50% at clinical onset, increasing with temporal disease progression, and 40% in control subjects. In blood, MSRV was detected in all MS patients, in most patients with inflammatory neurologic diseases, and rarely in healthy blood donors. MSRV may represent a marker of neurologic diseases of inflammatory origin.
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