Sardon, David and Blundell, Richard and Burrai, Giovanni Pietro and Alberti, Alberto and Tore, G. and Sanna Passino, Eraldo and Antuofermo, Elisabetta (2015) Absence of canine papillomavirus sequences in canine mammary tumours. Journal of comparative pathology, Vol. 152 (2-3), p. 172-176. ISSN 0021-9975. eISSN 1532-3129. Article.
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Human papillomaviruses (PVs) are found in human breast cancer tissue; however, it remains controversial as to whether these viruses play a role in the aetiology of this tumour. There has been minimal study of whether PVs are found in normal or abnormal mammary glands of animals. The present study investigated whether a PV sequence could be found in the mammary glands of 33 female dogs by rolling circle amplification and polymerase chain reaction. No PV DNA was found in normal or neoplastic canine mammary tissues, suggesting that canine PVs are probably not involved in the pathogenesis of canine mammary neoplasia.
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