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Moringa oleifera: study of phenolics and glucosinolates by mass spectrometry’

Maldini, Mariateresa and Maksoud, Salwa A. and Natella, Fausta and Montoro, Paola and Petretto, Giacomo Luigi and Foddai, Marzia and De Nicola, Gina Rosalinda and Chessa, Mario and Pintore, Giorgio Antonio Mario (2014) Moringa oleifera: study of phenolics and glucosinolates by mass spectrometry’. Journal of mass spectrometry, Vol. 49 (9), p. 900-910. ISSN 1076-5174. eISSN 1096-9888. Article.

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DOI: 10.1002/jms.3437

Abstract

Moringa oleifera is a medicinal plant and an excellent dietary source of micronutrients (vitamins and minerals) and health-promoting phytochemicals (phenolic compounds, glucosinolates and isothiocyanates). Glucosinolates and isothiocyanates are known to possess anti-carcinogenic and antioxidant effects and have attracted great interest from both toxicological and pharmacological points of view, as they are able to induce phase 2 detoxification enzymes and to inhibit phase 1 activation enzymes. Phenolic compounds possess antioxidant properties and may exert a preventative effect in regards to the development of chronic degenerative diseases.
The aim of this work was to assess the profile and the level of bioactive compounds in all parts of M. oleifera seedlings, by using different MS approaches. First, flow injection electrospray ionization mass spectrometry (FI-ESI-MS) fingerprinting techniques and chemometrics (PCA) were used to achieve the characterization of the different plant's organs in terms of profile of phenolic compounds and glucosinolates. Second, LC-MS and LC-MS/MS qualitative and quantitative methods were used for the identification and/or determination of phenolics and glucosinolates in M. oleifera.

Item Type:Article
ID Code:10319
Status:Published
Refereed:Yes
Uncontrolled Keywords:Moringa oleifera, glucosinolates, PCA, LC-MS, MRM
Subjects:Area 05 - Scienze biologiche > BIO/15 Biologia farmaceutica
Divisions:001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Chimica e Farmacia
Publisher:Wiley
ISSN:1076-5174
eISSN:1096-9888
Deposited On:17 Nov 2014 10:20

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