Delitala, Giuseppe and Masala, Antonio Giovanni Emilio and Alagna, Sergio and Devilla, Luisa (1976) Effect of metoclopramide on serum prolactin levels in humans. Clinical endocrinology, Vol. 5 (6), p. 731-734. ISSN 0300-0664. eISSN 1365-2265. Article.
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The effect of acute and chronic administration of metoclopramide on serum prolactin levels in normal subjects was studied. Metoclopramide 10 mg i.v. induced a prompt rise in serum prolactin levels in all subjects. At 180 min the levels remained high. Prolactin levels were markedly elevated during a 5 day course of treatment with metoclopramide in six subjects. It is suggested that metoclopramide could be used in the functional exploration of the hypothalamic-pituitary axis.
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