titoli, abstracts, parole chiave >>>
Outbreak of multidrug-resistant Acinetobacter baumannii in an intensive care unit

Dettori, Marco and Piana, Andrea Fausto and Deriu, Maria Grazia and Lo Curto, Paola and Cossu, Andrea and Musumeci, Rosario and Cocuzza, Clementina and Astone, Vito and Contu, Maria Antonietta and Sotgiu, Giovanni (2014) Outbreak of multidrug-resistant Acinetobacter baumannii in an intensive care unit. New microbiologica, Vol. 37 (2), p. 185-191. ISSN 1121-7138. Article.

Full text not available from this repository.

Alternative URLs:

Abstract

Acinetobacter baumannii is a ubiquitous microrganism often able to colonize and survive in different environments. Currently it is one of the most common pathogens responsible for nosocomial infections, including outbreaks, especially in long-term care facilities. The aim of this study was to show the results of an environmental investigation and genotyping analysis of multidrug-resistant Acinetobacter baumannii associated with an outbreak in an intensive care unit of a tertiary hospital located in Northern Sardinia, Italy.
Positive cultures of MDR Acinetobacter baumannii were reported during the month of June 2012, after the collection of biological samples from ten patients. Acinetobacter baumannii was isolated during the following environmental investigation from the headboard of two beds. All the strains were genotyped by performing multiplex PCR to identify the presence of genes encoding carbapenemases. The results showed specific bands of blaOXA-51-like gene and of the blaOXA-23-like gene.
PFGE highlighted minimal differences in genomic fingerprints, while the cluster analysis grouped the isolated microorganisms into two closely related clusters, characterized by Dice’s similarity coefficient equal to 95.1%. MLST showed that the strains belonged to ST31.
The results of the study highlight the need, especially in high-risk areas, to adopt strict hygiene practices, particularly hand hygiene, and to ensure an appropriate turnover of personal protective equipment, which could be responsible for the spread of biological agents, such as MDR Acinetobacter baumannii.

Item Type:Article
ID Code:10219
Status:Published
Refereed:Yes
Uncontrolled Keywords:Nosocomial outbreak, multidrug resistance, molecular epidemiology
Subjects:Area 06 - Scienze mediche > MED/42 Igiene generale e applicata
Area 06 - Scienze mediche > MED/01 Statistica medica
Divisions:002 Altri enti e centri di ricerca del Nord Sardegna > AOU -Azienda Ospedaliero Universitaria, Sassari
001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Architettura, Design e Urbanistica
001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Scienze Biomediche
002 Altri enti e centri di ricerca del Nord Sardegna > Azienda ASL3, Nuoro > Ospedale "San Francesco"
Publisher:Edizioni internazionali
ISSN:1121-7138
Deposited On:24 Oct 2014 10:57

I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore

Repository Staff Only: item control page