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Ranibizumab in retinal vein occlusion: treatment recommendations by an expert panel

Gerding, Heinrich and Monés, Jordi and Tadayoni, Ramin and Boscia, Francesco and Pearce, Ian and Priglinger, Siegfried (2014) Ranibizumab in retinal vein occlusion: treatment recommendations by an expert panel. British journal of ophthalmology, Vol. 99 (3), p. 297-304. ISSN 0007-1161. Article.

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DOI: 10.1136/bjophthalmol-2014-305041

Abstract

Retinal vein occlusion (RVO) is a common cause of retinal vascular disease, resulting in potentially irreversible loss of vision despite the existence of several therapeutic options. The humanised monoclonal antibody fragment ranibizumab binds to and inhibits vascular endothelial growth factor, a key driver of macular oedema in RVO. In 2010, ranibizumab was approved in the USA for the treatment of macular oedema in RVO and, in 2011, ranibizumab was approved in the European Union for the treatment of visual impairment caused by macular oedema secondary to RVO in branch and central RVO. Ranibizumab provides an additional therapeutic option for this complex disease: an option that was not fully considered during the preparation of current international guidelines. An expert panel was convened to critically evaluate the evidence for treatment with ranibizumab in patients with visual impairment caused by macular oedema secondary to RVO and to develop treatment recommendations, with the aim of assisting physicians to optimise patient treatment.

Item Type:Article
ID Code:10186
Status:Published
Refereed:Yes
Uncontrolled Keywords:Retinal vein occlusion (RVO), vision loss, ranibizumab
Subjects:Area 06 - Scienze mediche > MED/30 Malattie apparato visivo
Divisions:002 Altri enti e centri di ricerca del Nord Sardegna > AOU -Azienda Ospedaliero Universitaria, Sassari
001 Università di Sassari > 03 Istituti > Oftalmologia, Otorinolaringoiatria e Urologia
Publisher:British Medical Journal
ISSN:0007-1161
Deposited On:14 Oct 2014 10:46

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