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SPECT and PET serve as molecular imaging techniques and in vivo biomarkers for brain metastases

Palumbo, Barbara and Buresta, Tommaso and Nuvoli, Susanna Maria Francesca and Spanu, Angela and Schillaci, Orazio and Fravolini, Mario Luca and Palumbo, Isabella (2014) SPECT and PET serve as molecular imaging techniques and in vivo biomarkers for brain metastases. International Journal of Molecular Sciences, Vol. 15 (6), p. 9878-9893. eISSN 1422-0067. Article.

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DOI: 10.3390/ijms15069878

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Nuclear medicine techniques (single photon emission computerized tomography, SPECT, and positron emission tomography, PET) represent molecular imaging tools, able to provide in vivo biomarkers of different diseases. To investigate brain tumours and metastases many different radiopharmaceuticals imaged by SPECT and PET can be used. In this review the main and most promising radiopharmaceuticals available to detect brain metastases are reported. Furthermore the diagnostic contribution of the combination of SPECT and PET data with radiological findings (magnetic resonance imaging, MRI) is discussed.

Item Type:Article
ID Code:10099
Uncontrolled Keywords:Brain metastases, molecular imaging, PET, SPECT, MRI, fusion imaging
Subjects:Area 06 - Scienze mediche > MED/36 Diagnostica per immagini e radioterapia
Divisions:001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Medicina Clinica e Sperimentale
Publisher:Molecular Diversity Preservation International
Copyright Holders:© 2014 by the authors; licensee MDPI, Basel, Switzerland
Deposited On:15 Sep 2014 17:04

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