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Warns against unapproved ‘chelation therapy’

Crisponi, Guido and Nurchi, Valeria Marina and Lachowicz, Joanna I. and Crespo-Alonso, Miriam and Zoroddu, Maria Antonietta and Peana, Massimiliano Francesco (2014) Warns against unapproved ‘chelation therapy’. Journal of Biological Inorganic Chemistry, Vol. 19 (2 supplement), S711-S712 (AW 9). ISSN 0949-8257. eISSN 1432-1327. Article.

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DOI: 10.1007/s00775-014-1155-0

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Abstract

At Eurobic11 in Granada we presented a Keynote Lecture on chelation therapy, a consolidated medical procedure used primarily to hinder the effects of toxic metal ions on human tissues. Its application spans a broad spectrum of serious disorders, ranging from acute metal intoxication to genetic metal-overload. The use of chelating agents is compromised by a number of serious side effects, mainly attributable to perturbed equilibrium of essential metal ion homeostasis and dislocation of complexed metal ions to dangerous body sites. For this reason, chelation therapy has been limited to specific critical and otherwise untreatable conditions and it needs to be monitored within an appropriate clinical context.
In this meeting we want warn against the widespread fraudulent use of the term ‘‘chelation therapy’’ to take advantage of and make profit from people with tragic health problems. We believe that scientists working in this field have the corollary obligation to deter these frauds and to inform the scientific community of the possible side effects and complications of chelation therapy. This duty is all the more important if we consider the detrimental and even life threatening consequences that can occur in subjects with no clear clinical and laboratory evidence of metal intoxication. The aim of this communication is to present how this ‘‘false chelation therapy’’ developed and in which diseases it is currently applied.
This research was supported by the Regione Autonoma Sardegna [CRP-27564].

Item Type:Article
ID Code:10073
Status:Published
Refereed:Yes
Uncontrolled Keywords:Chelation therapy, toxic metal ions, human tissues
Subjects:Area 03 - Scienze chimiche > CHIM/03 Chimica generale e inorganica
Area 03 - Scienze chimiche > CHIM/01 Chimica analitica
Divisions:001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Chimica e Farmacia
Publisher:Springer Berlin / Heildelberg
ISSN:0949-8257
eISSN:1432-1327
Additional Information:Oral presentation at the 12. European Biological Inorganic Chemistry Conference, Zurich, Switzerland, August 24–28, 2014
Deposited On:12 Sep 2014 13:20

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