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Chemical and biological study on the essential oil of Artemisiacaerulescens L. ssp. densiflora (Viv.)

Petretto, Giacomo Luigi and Chessa, Mario and Piana, Andrea Fausto and Masia, Maria Dolores and Foddai, Marzia and Mangano, Giuseppe Salvatore and Culeddu, Nicola and Afifi, Fatma U. and Pintore, Giorgio Antonio Mario (2013) Chemical and biological study on the essential oil of Artemisiacaerulescens L. ssp. densiflora (Viv.). Natural Product Research, Vol. 27 (19), p. 1709-1715. ISSN 1478-6419. eISSN 1478-6427. Article.

Full text not available from this repository.

DOI: 10.1080/14786419.2012.749471

Abstract

Artemisia caerulescens L. ssp. densiflora (Viv.) is a wild shrub that grows in the archipelago of La Maddalena, Sardinia, Italy. The antifungal activity of the volatile oil of this sub-species has not been evaluated earlier. This study aimed to identify the main components of the essential oil of A. caerulescens L. ssp. densiflora and to investigate its antifungal activity. Identification of the different components of the essential oil obtained by hydrodistillation from A. caerulescens L. ssp. densiflora was done by both techniques: GC-MS and NMR analyses (1H, 13C, HSQC-NMR). Antifungal activity was evaluated by agar disc diffusion technique against environmental isolates of fungal strains: two yeasts (Rhodotorula spp., Candida spp.), three moulds (Aspergillus spp., Alternaria spp., Fusarium spp.) and a mixture of moulds. GC-MS analysis of the essential oil yielded 42 compounds, out of which, 26 compounds were identified. The main compound was identified as terpinen-4-ol (22%) followed by p-cymene (7.6%) and α-terpineol (3.02%). The significant inhibition spectrum of the essential oil of A. caerulescens L. ssp. densiflora can be considered as an alternative to common disinfectants.

Item Type:Article
ID Code:10042
Status:Published
Refereed:Yes
Uncontrolled Keywords:Artemisia densiflora, essential oil, antifungal activity, GC-MS, NMR, La Maddalena, Sardinia, Italy
Subjects:Area 06 - Scienze mediche > MED/42 Igiene generale e applicata
Area 05 - Scienze biologiche > BIO/15 Biologia farmaceutica
Divisions:001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Scienze Biomediche
001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Chimica e Farmacia
Publisher:Taylor & Francis
ISSN:1478-6419
eISSN:1478-6427
Deposited On:28 Aug 2014 13:26

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